Prince Edward County is located in Southern Ontario on a large irregular headland or littoral at the eastern end of Lake Ontario, just west of the head of the St. Lawrence River. This headland (officially named Prince Edward County in 1792) is surrounded on the north and east by the Bay of Quinte. As the Murray Canal now connects the bay to Lake Ontario across the only land connection, the county is technically an island.
The county's relatively mild climate due to the influence of Lake Ontario has led to the establishment of about 50 vineyards and close to a dozen wineries. The lake effect from Lake Ontario results in heavier snowfall than in neighbouring counties.